CKR-5(Phospho Ser349) Polyclonal Antibody, 50ul Lysosome The integrin subunit beta 2

The integrin subunit beta 2 plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency

It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN

Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction

The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins)

Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling

CKR-5(Phospho Ser349) Polyclonal Antibody, 50ul Lysosome The integrin subunit beta 2This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co receptor for macrophage tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include