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E-cadherin Monoclonal Antibody, 100ul[BT-MCA0453] Peptide Library a state which is disrupted

SKU: 24534765486

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E-cadherin Monoclonal Antibody, 100ul[BT-MCA0453] Peptide Library a state which is disruptedThis gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated

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Description

a state which is disrupted by inhibition of this novel serine protease

Allelic variants are associated with prostate and brain cancer susceptibility

Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD

and severe mental retardation

The encoded protein is necessary for p53-mediated caspase activation and apoptosis

E-cadherin Monoclonal Antibody, 100ul[BT-MCA0453] Peptide Library a state which is disruptedThis gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated

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