MIA3 Polyclonal Antibody, 100ul General Lab Use Guanine nucleotide exchange factors (GEFs)

Guanine nucleotide exchange factors (GEFs) such as ARHGEF19 accelerate the GTPase activity of Rho GTPases (see RHOA

Component of the NF-kappa-B p52-c-Rel complex

suggesting that its substrate may carry its own oxygen

The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family

The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex

MIA3 Polyclonal Antibody, 100ul General Lab Use Guanine nucleotide exchange factors (GEFs)Although 2 transmembrane domains are predicted, PubMed: 19269366 showed that it only contains one transmembrane domain. The other predicted transmembrane region is probably a hairpin type region embedded into the membrane, which does not cross the membrane. It is unclear which of the 2 predicted transmembrane regions is the transmembrane or the hairpin type region.,The proline rich region (PRD) mediates the interaction with COPII coat subunits Sec23