Synuclein-Beta Polyclonal Antibody, 50ul Antibody Humanization Increased autoantibody titer against human

Increased autoantibody titer against human calreticulin is found in infants with complete congenital heart block of both the IgG and IgM classes

This protein is located in the nucleus

An important paralog of this gene is SLC30A4

This gene utilizes alternative polyadenylation signals and has multiple pseudogenes

The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking

Synuclein-Beta Polyclonal Antibody, 50ul Antibody Humanization Increased autoantibody titer against humanSNCB encodes a member of a small family of proteins that inhibit phospholipase D2 and may function in neuronal plasticity. The Beta synuclein is abundant in lesions of patients with Alzheimer disease. A mutation in this gene was found in individuals with dementia with Lewy bodies. Alternative splicing results in multiple transcript variants.