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In February 2025, researchers published findings in JAMA Psychiatry from the first randomized, placebo-controlled clinical trial specifically designed to study this phenomenon

Strategies for older women: Work with your fertility specialist to explore options like shorter optimization periods of 3-4 months on GLP-1s rather than 6 months, or potentially using a shorter washout if appropriate for your situation2 months instead of 3 (this decision should be made with your doctors guidance)

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This prevents cold air loss andprotects sensitive medications like Insulin, Zepbound, and Mounjaro from temperaturefluctuations

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